PDBe 2qms

X-ray diffraction
2.1Å resolution

Crystal structure of a signaling molecule

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Growth factor receptor-bound protein 7 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 120 amino acids
Theoretical weight: 13.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14451 (Residues: 415-532; Coverage: 22%)
Gene name: GRB7
Sequence domains: SH2 domain
Structure domains: SHC Adaptor Protein

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P212121
Unit cell:
a: 62.649Å b: 63.904Å c: 105.685Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.201 0.255
Expression system: Escherichia coli