PDBe 2qm4

X-ray diffraction
2.3Å resolution

Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Non-homologous end-joining factor 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 235 amino acids
Theoretical weight: 27.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9H9Q4 (Residues: 1-233; Coverage: 78%)
Gene names: NHEJ1, XLF
Sequence domains: XLF-Cernunnos, XRcc4-like factor, NHEJ component
Structure domains:

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 63.736Å b: 92.913Å c: 103.693Å
α: 90° β: 106.22° γ: 90°
R R work R free
0.185 0.182 0.239
Expression system: Escherichia coli