PDBe 2qlu

X-ray diffraction
2Å resolution

Crystal structure of Activin receptor type II kinase domain from human

Released:

Function and Biology Details

Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Activin receptor type-2B Chain: A
Molecule details ›
Chain: A
Length: 314 amino acids
Theoretical weight: 35.8 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q13705 (Residues: 190-487; Coverage: 60%)
Gene name: ACVR2B
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P43212
Unit cell:
a: 98.217Å b: 98.217Å c: 71.345Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.216 0.283