PDBe 2qg5

X-ray diffraction
2.3Å resolution

Cryptosporidium parvum calcium dependent protein kinase cgd7_1840

Released:
Entry authors: Lunin VV, Wernimont AK, Lew J, Wasney G, Kozieradzki I, Vedadi M, Bochkarev A, Arrowsmith CH, Sundstrom M, Weigelt J, Edwards AE, Hui R, Artz J, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands Chains: A, B, D
Molecule details ›
Chains: A, B, D
Length: 294 amino acids
Theoretical weight: 34.09 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5CYL9 (Residues: 197-472; Coverage: 41%)
Gene name: cgd7_1840
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2
Unit cell:
a: 138.178Å b: 86.476Å c: 87.965Å
α: 90° β: 96.37° γ: 90°
R-values:
R R work R free
0.224 0.22 0.286
Expression system: Escherichia coli