PDBe 2qc9

X-ray diffraction
2.35Å resolution

Mouse Notch 1 Ankyrin Repeat Intracellular Domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Notch 1 intracellular domain Chains: A, B
Molecule details ›
Chains: A, B
Length: 210 amino acids
Theoretical weight: 23.13 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q01705 (Residues: 1899-2106; Coverage: 8%)
Gene names: Motch, Notch1
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P65
Unit cell:
a: 98.203Å b: 98.203Å c: 108.703Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.173 0.173 0.228
Expression system: Escherichia coli BL21(DE3)