PDBe 2qc8

X-ray diffraction
2.6Å resolution

Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamine synthetase Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 384 amino acids
Theoretical weight: 43.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15104 (Residues: 5-365; Coverage: 97%)
Gene names: GLNS, GLUL
Sequence domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 181.21Å b: 126.08Å c: 188.17Å
α: 90° β: 92.14° γ: 90°
R-values:
R R work R free
0.168 0.166 0.217
Expression system: Escherichia coli