PDBe 2qa2

X-ray diffraction
2.7Å resolution

Crystal structure of CabE, an aromatic hydroxylase from angucycline biosynthesis, determined to 2.7 A resolution

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polyketide oxygenase CabE Chain: A
Molecule details ›
Chain: A
Length: 499 amino acids
Theoretical weight: 53.64 KDa
Source organism: Streptomyces
Expression system: Escherichia coli
UniProt:
  • Canonical: D0VWY3 (Residues: 1-474; Coverage: 100%)
Gene name: cabe
Sequence domains: FAD binding domain
Structure domains: FAD/NAD(P)-binding domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P6522
Unit cell:
a: 133.1Å b: 133.1Å c: 166.8Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.234 0.274
Expression system: Escherichia coli