PDBe 2q3b

X-ray diffraction
1.8Å resolution

1.8 A Resolution Crystal Structure of O-Acetylserine Sulfhydrylase (OASS) Holoenzyme From MYCOBACTERIUM TUBERCULOSIS

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
O-acetylserine sulfhydrylase Chain: A
Molecule details ›
Chain: A
Length: 313 amino acids
Theoretical weight: 33.3 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WP55 (Residues: 1-310; Coverage: 100%)
Gene names: MTCY98.03, Rv2334, cysK, cysK1
Sequence domains: Pyridoxal-phosphate dependent enzyme
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P41212
Unit cell:
a: 70.991Å b: 70.991Å c: 179.624Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.174 0.192
Expression system: Escherichia coli BL21(DE3)