› 2plu

X-ray diffraction
1.82Å resolution

Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120

Released:
DOI: 10.2210/pdb2plu/pdb
PDB entry 2plu coloured by chain, front view.
PDB entry 2plu coloured by chain, side view.
PDB entry 2plu coloured by chain, top view.
Source organism: Cryptosporidium parvum Iowa II
Entry authors: Wernimont AK, Lew J, Hills T, Kozieradzki I, Lin YH, Hassanali A, Zhao Y, Schapira M, Arrowsmith CH, Edwards AM, Weigelt J, Sundstrom M, Bochkarev A, Hui R, Artz JD, Xiao T, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107146 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase Chain: A
Molecule details ›
Chain: A
Length: 186 amino acids
Theoretical weight: 20.33 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli
UniProt:
  • Canonical: A3FQA7 (Residues: 3-170; Coverage: 98%)
Gene name: cgd2_4120
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P3121
Unit cell:
a: 56.856Å b: 56.856Å c: 107.255Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.175 0.217
Expression system: Escherichia coli

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