PDBe 2pla

X-ray diffraction
2.51Å resolution

Crystal structure of human glycerol-3-phosphate dehydrogenase 1-like protein

Released:
Source organism: Homo sapiens
Entry authors: Uppenberg J, Smee C, Hozjan V, Kavanagh K, Bunkoczi G, Papagrigoriou E, Pike ACW, Ugochukwu E, Umeano C, von Delft F, Weigelt J, Arrowsmith CH, Edwards A, Sundstrom M, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycerol-3-phosphate dehydrogenase 1-like protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 349 amino acids
Theoretical weight: 38.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8N335 (Residues: 1-349; Coverage: 99%)
Gene names: GPD1L, KIAA0089
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 2 x NAD
2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P3121
Unit cell:
a: 139.1Å b: 139.1Å c: 109.62Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.175 0.212
Expression system: Escherichia coli BL21(DE3)