2pf5

X-ray diffraction
1.9Å resolution

Crystal Structure of the Human TSG-6 Link Module

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-161341 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor-inducible gene 6 protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 98 amino acids
Theoretical weight: 10.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P98066 (Residues: 36-133; Coverage: 38%)
Gene names: TNFAIP6, TSG6
Sequence domains: Extracellular link domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: C2
Unit cell:
a: 134.816Å b: 75.87Å c: 90.674Å
α: 90° β: 103.42° γ: 90°
R-values:
R R work R free
0.196 0.194 0.226
Expression system: Escherichia coli BL21(DE3)