› 2p9t

X-ray diffraction
2Å resolution

Crystal Structure of Phosphoglycerate Kinase-2 bound to 3-phosphoglycerate

Released:
DOI: 10.2210/pdb2p9t/pdb
PDB entry 2p9t coloured by chain, front view.
PDB entry 2p9t coloured by chain, side view.
PDB entry 2p9t coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
X-ray analysis of phosphoglycerate kinase 2, a sperm-specific isoform from Mus musculus.
Sawyer GM, Monzingo AF, Poteet EC, O'Brien DA, Robertus JD
Proteins 71 1134-44 (2008)
PMID: 18004764

Function and Biology Details

Reaction catalysed: 
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140540 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoglycerate kinase 2 Chain: A
Molecule details ›
Chain: A
Length: 416 amino acids
Theoretical weight: 44.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P09041 (Residues: 2-417; Coverage: 100%)
Gene names: Pgk-2, Pgk2
Sequence domains: Phosphoglycerate kinase
Structure domains: Phosphoglycerate kinase, N-terminal domain

Ligands and Environments

1 bound ligand:
Ligand 3PG 1 x 3PG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P21
Unit cell:
a: 42.1Å b: 64.3Å c: 72.2Å
α: 90° β: 97.8° γ: 90°
R-values:
R R work R free
0.221 0.221 0.269
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Moonlighting Proteins: The Case of the Hexokinases.
Rodríguez-Saavedra et al. (2021)
2 more

1 mention without citation

A Code Within a Code: How Codons Fine-Tune Protein Folding in the Cell.
Komar AA. (2021)