PDBe 2p0c

X-ray diffraction
2.4Å resolution

Catalytic Domain of the Proto-oncogene Tyrosine-protein Kinase MER

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase Mer Chains: A, B
Molecule details ›
Chains: A, B
Length: 313 amino acids
Theoretical weight: 35.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12866 (Residues: 570-864; Coverage: 30%)
Gene names: MER, MERTK
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 52.47Å b: 90.057Å c: 69.253Å
α: 90° β: 102.44° γ: 90°
R-values:
R R work R free
0.208 0.204 0.274
Expression system: Escherichia coli