PDBe 2ozo

X-ray diffraction
2.6Å resolution

Autoinhibited intact human ZAP-70

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase ZAP-70 Chain: A
Molecule details ›
Chain: A
Length: 613 amino acids
Theoretical weight: 69.35 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P43403 (Residues: 1-606; Coverage: 98%)
Gene names: SRK, ZAP70
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P1
Unit cell:
a: 48.297Å b: 52.929Å c: 69.331Å
α: 105.91° β: 92.94° γ: 103.72°
R-values:
R R work R free
0.26 0.22 0.29
Expression system: Spodoptera frugiperda