PDBe 2oxx

X-ray diffraction
2.3Å resolution

Protein kinase CK2 in complex with tetrabromobenzoimidazole derivatives K17, K22 and K32


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Casein kinase II subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 332 amino acids
Theoretical weight: 39.29 KDa
Source organism: Zea mays
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P28523 (Residues: 1-332; Coverage: 100%)
Gene name: ACK2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID13
Spacegroup: C2
Unit cell:
a: 141.348Å b: 60.524Å c: 45.492Å
α: 90° β: 102.82° γ: 90°
R R work R free
0.217 0.214 0.27
Expression system: Escherichia coli BL21(DE3)