PDBe 2om9

X-ray diffraction
2.8Å resolution

Ajulemic acid, a synthetic cannabinoid bound to PPAR gamma


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Peroxisome proliferator-activated receptor gamma Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 278 amino acids
Theoretical weight: 31.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P37231 (Residues: 232-505; Coverage: 54%)
Gene names: NR1C3, PPARG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P1
Unit cell:
a: 62.344Å b: 78.139Å c: 104.231Å
α: 100.1° β: 106.41° γ: 90.01°
R R work R free
0.219 0.217 0.267
Expression system: Escherichia coli BL21(DE3)