PDBe 2oju

X-ray diffraction
2.4Å resolution

X-ray structure of complex of human cyclophilin J with cyclosporin A

Entry authors: Xia Z, Huang L

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Molecule details ›
Chains: C, D
Length: 11 amino acids
Theoretical weight: 1.22 KDa
Source organism: Tolypocladium inflatum
Expression system: Not provided
Peptidyl-prolyl cis-trans isomerase-like 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 167 amino acids
Theoretical weight: 18.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9H2H8 (Residues: 1-161; Coverage: 100%)
Gene name: PPIL3
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

Ligands and Environments

No bound ligands

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P3121
Unit cell:
a: 64.387Å b: 64.387Å c: 200.943Å
α: 90° β: 90° γ: 120°
R R work R free
0.193 0.193 0.237
Expression systems:
  • Not provided
  • Escherichia coli