PDBe 2ogv

X-ray diffraction
2.7Å resolution

Crystal Structure of the Autoinhibited Human c-Fms Kinase Domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Macrophage colony-stimulating factor 1 receptor Chain: A
Molecule details ›
Chain: A
Length: 317 amino acids
Theoretical weight: 35.79 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P07333 (Residues: 543-918; Coverage: 33%)
Gene names: CSF1R, FMS
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: P21212
Unit cell:
a: 104.253Å b: 57.298Å c: 56.785Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.206 0.279
Expression system: Spodoptera frugiperda