Structure analysis

crystal structure of aminoquinazoline 36 bound to Lck

X-ray diffraction
2.3Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: monomeric
Accessible surface area: 12000 Å2
Buried surface area: 1200 Å2
Dissociation area: 600 Å2
Dissociation energy (ΔGdiss): -7 kcal/mol
Dissociation entropy (TΔSdiss): 6 kcal/mol
Interface energy (ΔGint): 4 kcal/mol
Symmetry number: 1
Assembly 2
Download    3D Visualisation
Multimeric state: monomeric
Accessible surface area: 12100 Å2
Buried surface area: 1200 Å2
Dissociation area: 600 Å2
Dissociation energy (ΔGdiss): -7 kcal/mol
Dissociation entropy (TΔSdiss): 6 kcal/mol
Interface energy (ΔGint): 4 kcal/mol
Symmetry number: 1

Macromolecules

Search similar proteins