Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Mechanosensitive ion channel MscS, C-terminal domain superfamily
- Mechanosensitive ion channel MscS, conserved site
- Mechanosensitive ion channel MscS, beta-domain superfamily
- LSM domain superfamily
- Mechanosensitive ion channel MscS
- Mechanosensitive ion channel MscS, transmembrane-2
- Mechanosensitive ion channel, conserved TM helix
- Mechanosensitive ion channel MscS, archaea/bacteria type
Structure analysis Details
Assembly composition:
homo heptamer (preferred)
Assembly name:
Small-conductance mechanosensitive channel (preferred)
PDBe Complex ID:
PDB-CPX-142906 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Small-conductance mechanosensitive channel
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 306 amino acids
Theoretical weight: 33.09 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 306 amino acids
Theoretical weight: 33.09 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P0C0S1 (Residues: 1-286; Coverage: 100%)
Sequence domains:
- Mechanosensitive ion channel, conserved TM helix
- Mechanosensitive ion channel, transmembrane helices 2/3
- Mechanosensitive ion channel, beta-domain
- Mechanosensitive ion channel MscS, C-terminal
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL9-2
Spacegroup:
P43212
Expression system: Escherichia coli BL21(DE3)
