PDBe 2o8y

X-ray diffraction
2.4Å resolution

Apo IRAK4 Kinase Domain

Released:
Source organism: Homo sapiens
Entry authors: Boriack-Sjodin PA, Mol C

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-1 receptor-associated kinase 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 298 amino acids
Theoretical weight: 34 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9NWZ3 (Residues: 163-460; Coverage: 65%)
Gene name: IRAK4
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

No bound ligands

2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: I222
Unit cell:
a: 90.15Å b: 118.64Å c: 140.71Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.246 0.244 0.289
Expression system: Spodoptera frugiperda