PDBe 2nzj

X-ray diffraction
2.5Å resolution

The crystal structure of REM1 in complex with GDP

Released:
Source organism: Homo sapiens
Entry authors: Turnbull AP, Papagrigoriou E, Ugochukwu E, Elkins JM, Soundararajan M, Yang X, Gorrec F, Umeano C, Salah E, Burgess N, Johansson C, Berridge G, Gileadi O, Bray J, Marsden B, Watts S, von Delft F, Weigelt J, Edwards A, Arrowsmith CH, Sundstrom M, Doyle D, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTP-binding protein REM 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 175 amino acids
Theoretical weight: 19.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75628 (Residues: 79-251; Coverage: 58%)
Gene names: GES, REM, REM1
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 43.64Å b: 102.284Å c: 165.565Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.225 0.28
Expression system: Escherichia coli