› 2mrd

Solution NMR

Solution structure of human Ca2+-loaded S100A4 cys-free mutant

Released:
DOI: 10.2210/pdb2mrd/pdb
PDB entry 2mrd coloured by chain, ensemble of 20 models, front view.
PDB entry 2mrd coloured by chain, ensemble of 20 models, side view.
PDB entry 2mrd coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The solution structure of human calcium-bound S100A4 mutated at four cysteine loci.
Cho CC, Hung KW, Gorja DR, Yu C
J Biomol NMR 62 233-8 (2015)
PMID: 25855140

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150750 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein S100-A4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 101 amino acids
Theoretical weight: 11.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P26447 (Residues: 1-101; Coverage: 100%)
Gene names: CAPL, MTS1, S100A4
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 41%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Multilevel Changes in Protein Dynamics upon Complex Formation of the Calcium-Loaded S100A4 with a Nonmuscle Myosin IIA Tail Fragment.
Pálfy et al. (2016)

4 mentions without citation

Zooming into the Dark Side of Human Annexin-S100 Complexes: Dynamic Alliance of Flexible Partners.
Weisz et al. (2020)
3 more