PDBe 2mb3

Solution NMR

Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA_(5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*A)-3') Chain: A
Molecule details ›
Chain: A
Length: 24 nucleotides
Theoretical weight: 7.59 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 39%
Refinement method: DGSA-distance geometry simulated annealing, simulated annealing, molecular dynamics
Chemical shifts: BMR19387  
Expression system: Not provided