› › Structure analysis

40-residue beta-amyloid fibril derived from Alzheimer's disease brain

Solid-state NMR
PDB entry 2m4j coloured by chain, ensemble of 20 models, front view.
PDB entry 2m4j coloured by chain, ensemble of 20 models, side view.
PDB entry 2m4j coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
homo nonamer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Soluble APP-beta
hide full assembly name
Multimeric state: homo nonamer
Accessible surface area: 18129.49 Å2
Buried surface area: 25494.01 Å2
Dissociation area: 3,287.83 Å2
Dissociation energy (ΔGdiss): 18.15 kcal/mol
Dissociation entropy (TΔSdiss): 24.82 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-138405

Macromolecules

Amyloid-beta protein 40
Chains: A, B, C, D, E, F, G, H, I
Length: 40 amino acids
Theoretical weight: 4.34 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P05067 (Residues: 672-711; Coverage: 5%)
Gene names: A4, AD1, APP
Pfam: Beta-amyloid peptide (beta-APP)
InterPro:
Amyloid-beta protein 40 in PDB entry 2m4j, assembly 1, front view.
Amyloid-beta protein 40 in PDB entry 2m4j, assembly 1, side view.
Amyloid-beta protein 40 in PDB entry 2m4j, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links