PDBe 2m34

Solution NMR

NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens

Released:
Source organism: Homo sapiens
Entry authors: Proudfoot A, Serrano P, Geralt M, Wuthrich K, Partnership for Stem Cell Biology (STEMCELL), Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeobox protein GBX-1 Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 8.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14549 (Residues: 256-325; Coverage: 19%)
Gene name: GBX1
Sequence domains: Homeobox domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: molecular dynamics
Chemical shifts: BMR18944  
Expression system: Escherichia coli