Function and Biology

The solution NMR structure of the transmembrane C-terminal domain of the amyloid precursor protein (C99)

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: membrane

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF10515
Domain description: Beta-amyloid precursor protein C-terminus
Occurring in:
  1. C99
The deposited structure of PDB entry 2lp1 contains 1 copy of Pfam domain PF10515 (Beta-amyloid precursor protein C-terminus) in C99. Showing 1 copy in chain A.

PF03494
Domain description: Beta-amyloid peptide (beta-APP)
Occurring in:
  1. C99
The deposited structure of PDB entry 2lp1 contains 1 copy of Pfam domain PF03494 (Beta-amyloid peptide (beta-APP)) in C99. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013803
Domain description: Amyloidogenic glycoprotein, amyloid-beta peptide
Occurring in:
  1. C99
IPR008155
Domain description: Amyloidogenic glycoprotein
Occurring in:
  1. C99
IPR019745
Domain description: Amyloidogenic glycoprotein, intracellular domain, conserved site
Occurring in:
  1. C99
IPR011993
Domain description: PH-like domain superfamily
Occurring in:
  1. C99
IPR019543
Domain description: Beta-amyloid precursor protein C-terminal
Occurring in:
  1. C99
IPR037071
Domain description: Amyloidogenic glycoprotein, amyloid-beta peptide superfamily
Occurring in:
  1. C99