› 2lc5

Solution NMR

Calmodulin-like Protein from Entamoeba histolytica: Solution Structure and Calcium-Binding Properties of a Partially Folded Protein

Released:
DOI: 10.2210/pdb2lc5/pdb
PDB entry 2lc5 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lc5 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lc5 coloured by chain, ensemble of 20 models, top view.
Source organism: Entamoeba histolytica HM-1:IMSS
Primary publication:
Calmodulin-like Protein from Entamoeba histolytica: Solution Structure and Calcium-Binding Properties of a Partially Folded Protein.
Rout AK, Padhan N, Barnwal RP, Bhattacharya A, Chary KV
Biochemistry (2010)
PMID: 21114322

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111324 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
EF-hand domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 151 amino acids
Theoretical weight: 17.26 KDa
Source organism: Entamoeba histolytica HM-1:IMSS
Expression system: Escherichia coli
UniProt:
  • Canonical: C4M0U8 (Residues: 1-151; Coverage: 100%)
Gene name: EHI_100270
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 77%
Refinement method: DGSA-distance geometry simulated annealing, DISTANCE GEOMETRY, SIMULATED ANNEALING
Expression system: Escherichia coli

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Citations

1 review citation

Nuclear transport in Entamoeba histolytica: knowledge gap and therapeutic potential.
Gwairgi et al. (2018)
9 other articles

2 mentions without citation

Structural and functional diversity of Entamoeba histolytica calcium-binding proteins.
Kumar et al. (2020)
1 more