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Solution structure of the Zalpha domain mutant of ADAR1 (N43A,Y47A)

Solution NMR
PDB entry 2l54 coloured by chain, ensemble of 20 models, front view.
PDB entry 2l54 coloured by chain, ensemble of 20 models, side view.
PDB entry 2l54 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Double-stranded RNA-specific adenosine deaminase
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-157286

Macromolecules

Double-stranded RNA-specific adenosine deaminase
Chain: A
Length: 63 amino acids
Theoretical weight: 6.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P55265 (Residues: 136-198; Coverage: 5%)
Gene names: ADAR, ADAR1, DSRAD, G1P1, IFI4
Pfam: Adenosine deaminase z-alpha domain
InterPro:
CATH: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Double-stranded RNA-specific adenosine deaminase in PDB entry 2l54, assembly 1, front view.
Double-stranded RNA-specific adenosine deaminase in PDB entry 2l54, assembly 1, side view.
Double-stranded RNA-specific adenosine deaminase in PDB entry 2l54, assembly 1, top view.
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