PDBe 2l54

Solution NMR

Solution structure of the Zalpha domain mutant of ADAR1 (N43A,Y47A)

Released:
Source organism: Homo sapiens
Primary publication:
Alternate rRNA secondary structures as regulators of translation.
Nat. Struct. Mol. Biol. 18 169-76 (2011)
PMID: 21217697

Function and Biology Details

Reaction catalysed:
Adenine in double-stranded RNA + H(2)O = hypoxanthine in double-stranded RNA + NH(3)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Double-stranded RNA-specific adenosine deaminase Chain: A
Molecule details ›
Chain: A
Length: 63 amino acids
Theoretical weight: 6.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P55265 (Residues: 136-198; Coverage: 5%)
Gene names: ADAR, ADAR1, DSRAD, G1P1, IFI4
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli