PDBe 2l2t

Solution NMR

Solution NMR structure of the ErbB4 dimeric membrane domain

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ERBB4 intracellular domain Chains: A, B
Molecule details ›
Chains: A, B
Length: 44 amino acids
Theoretical weight: 4.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15303 (Residues: 642-685; Coverage: 3%)
Gene names: ERBB4, HER4

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)