PDBe 2kz5

Solution NMR

Solution NMR Structure of Transcription factor NF-E2 subunit's DNA binding domain from Homo sapiens, Northeast Structural Genomics Consortium Target HR4653B

Source organism: Homo sapiens
Entry authors: Liu G, Janjua H, Xiao R, Ciccosanti C, Shastry R, Acton TB, Tong S, Everett JK, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Transcription factor NF-E2 45 kDa subunit Chain: A
Molecule details ›
Chain: A
Length: 91 amino acids
Theoretical weight: 10.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q16621 (Residues: 214-293; Coverage: 21%)
Gene name: NFE2
Structure domains: A DNA-binding domain in eukaryotic transcription factors

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 81%
Refinement method: distance geometry, simulated annealing, molecular dynamics, torsion angle dynamics
Chemical shifts: BMR16998  
Expression system: Escherichia coli BL21(DE3)