› 2kxp

Solution NMR

Solution NMR structure of V-1 bound to capping protein (CP)

Released:
DOI: 10.2210/pdb2kxp/pdb
PDB entry 2kxp coloured by chain, ensemble of 10 models, front view.
PDB entry 2kxp coloured by chain, ensemble of 10 models, side view.
PDB entry 2kxp coloured by chain, ensemble of 10 models, top view.
Source organisms:
Entry authors: Zwolak A, Fujiwara I, Hammer III JA, Tjandra N

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-146477 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
F-actin-capping protein subunit alpha-1 Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.72 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P13127 (Residues: 7-281; Coverage: 96%)
Gene name: CAPZA1
Sequence domains: F-actin capping protein alpha subunit
Structure domains:
F-actin-capping protein subunit beta isoforms 1 and 2 Chain: B
Molecule details ›
Chain: B
Length: 270 amino acids
Theoretical weight: 30.54 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P14315 (Residues: 2-271; Coverage: 98%)
Gene name: CAPZB
Sequence domains: F-actin capping protein, beta subunit
Structure domains:
Myotrophin Chain: C
Molecule details ›
Chain: C
Length: 118 amino acids
Theoretical weight: 12.88 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P62774 (Residues: 1-118; Coverage: 100%)
Gene names: Gcdp, Mtpn
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli

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