PDBe 2kxp

Solution NMR

Solution NMR structure of V-1 bound to capping protein (CP)

Released:
Source organisms:
Entry authors: Zwolak A, Fujiwara I, Hammer III JA, Tjandra N

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Myotrophin Chain: C
Molecule details ›
Chain: C
Length: 118 amino acids
Theoretical weight: 12.88 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P62774 (Residues: 1-118; Coverage: 100%)
Gene names: Gcdp, Mtpn
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
F-actin-capping protein subunit alpha-1 Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.72 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P13127 (Residues: 7-281; Coverage: 96%)
Gene name: CAPZA1
F-actin-capping protein subunit beta isoforms 1 and 2 Chain: B
Molecule details ›
Chain: B
Length: 270 amino acids
Theoretical weight: 30.54 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P14315 (Residues: 2-271; Coverage: 98%)
Gene name: CAPZB
Sequence domains: F-actin capping protein, beta subunit
Structure domains: Capz alpha-1 subunit

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli