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Solution NMR structure of human ubiquitin specific protease Usp7 UBL domain (residues 537-664). NESG target hr4395c/ SGC-Toronto

Solution NMR
PDB entry 2kvr coloured by chain, ensemble of 20 models, front view.
PDB entry 2kvr coloured by chain, ensemble of 20 models, side view.
PDB entry 2kvr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Ubiquitin carboxyl-terminal hydrolase 7
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Multimeric state: monomeric
Accessible surface area: 8557.0 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-187973

Macromolecules

Ubiquitin carboxyl-terminal hydrolase 7
Chain: A
Length: 130 amino acids
Theoretical weight: 15.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q93009 (Residues: 537-664; Coverage: 12%)
Gene names: HAUSP, USP7
InterPro: Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain
Ubiquitin carboxyl-terminal hydrolase 7 in PDB entry 2kvr, assembly 1, front view.
Ubiquitin carboxyl-terminal hydrolase 7 in PDB entry 2kvr, assembly 1, side view.
Ubiquitin carboxyl-terminal hydrolase 7 in PDB entry 2kvr, assembly 1, top view.
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