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Solution NMR Structure of the SH3 Domain from the p85beta subunit of Phosphatidylinositol 3-kinase from H.sapiens, Northeast Structural Genomics Consortium Target HR5531E

Solution NMR
PDB entry 2kt1 coloured by chain, ensemble of 20 models, front view.
PDB entry 2kt1 coloured by chain, ensemble of 20 models, side view.
PDB entry 2kt1 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Phosphatidylinositol 3-kinase regulatory subunit beta
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Multimeric state: monomeric
Accessible surface area: 5284.93 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-126293

Macromolecules

Phosphatidylinositol 3-kinase regulatory subunit beta
Chain: A
Length: 88 amino acids
Theoretical weight: 9.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00459 (Residues: 1-80; Coverage: 11%)
Gene name: PIK3R2
InterPro:
CATH: SH3 Domains
Phosphatidylinositol 3-kinase regulatory subunit beta in PDB entry 2kt1, assembly 1, front view.
Phosphatidylinositol 3-kinase regulatory subunit beta in PDB entry 2kt1, assembly 1, side view.
Phosphatidylinositol 3-kinase regulatory subunit beta in PDB entry 2kt1, assembly 1, top view.
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