PDBe 2kt1

Solution NMR

Solution NMR Structure of the SH3 Domain from the p85beta subunit of Phosphatidylinositol 3-kinase from H.sapiens, Northeast Structural Genomics Consortium Target HR5531E

Released:
Source organism: Homo sapiens
Entry authors: Aramini JM, Ma L, Schauder C, Everett JK, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3-kinase regulatory subunit beta Chain: A
Molecule details ›
Chain: A
Length: 88 amino acids
Theoretical weight: 9.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00459 (Residues: 1-80; Coverage: 11%)
Gene name: PIK3R2
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: simulated annealing, null
Chemical shifts: BMR16681  
Expression system: Escherichia coli BL21(DE3)