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solution structure of Helicobacter pylori SlyD

Source organism: Helicobacter pylori
Biochemical function: peptidyl-prolyl cis-trans isomerase activity
Biological process: not assigned
Cellular component: not assigned

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EC 5.2.1.8: Peptidylprolyl isomerase

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0)
Systematic name:
Peptidylproline cis-trans-isomerase
Alternative Name(s):
  • Cyclophilin
  • PPIase
  • Peptide bond isomerase
  • Peptidyl-prolyl cis-trans isomerase
  • Peptidylprolyl cis-trans isomerase
  • Rotamase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00254
Domain description: FKBP-type peptidyl-prolyl cis-trans isomerase
Occurring in:
  1. FKBP-type peptidyl-prolyl cis-trans isomerase SlyD
The deposited structure of PDB entry 2kr7 contains 1 copy of Pfam domain PF00254 (FKBP-type peptidyl-prolyl cis-trans isomerase) in FKBP-type peptidyl-prolyl cis-trans isomerase SlyD. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001179
Domain description: FKBP-type peptidyl-prolyl cis-trans isomerase domain
Occurring in:
  1. FKBP-type peptidyl-prolyl cis-trans isomerase SlyD
IPR046357
Domain description: Peptidyl-prolyl cis-trans isomerase domain superfamily
Occurring in:
  1. FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

Structure domains

CATH CATH domains
3.10.50.40
Class: Alpha Beta
Architecture: Roll
Topology: Chitinase A; domain 3
Homology: Chitinase A; domain 3
Occurring in:
  1. FKBP-type peptidyl-prolyl cis-trans isomerase SlyD
The deposited structure of PDB entry 2kr7 contains 1 copy of CATH domain 3.10.50.40 (Chitinase A; domain 3) in FKBP-type peptidyl-prolyl cis-trans isomerase SlyD. Showing 1 copy in chain A.
2.40.10.330
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Thrombin, subunit H
Homology: Thrombin, subunit H
Occurring in:
  1. FKBP-type peptidyl-prolyl cis-trans isomerase SlyD
The deposited structure of PDB entry 2kr7 contains 1 copy of CATH domain 2.40.10.330 (Thrombin, subunit H) in FKBP-type peptidyl-prolyl cis-trans isomerase SlyD. Showing 1 copy in chain A.

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