PDBe 2klu

Solution NMR

NMR structure of the transmembrane and cytoplasmic domains of human CD4

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell surface glycoprotein CD4 Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 7.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01730 (Residues: 397-458; Coverage: 14%)
Gene name: CD4
Sequence domains: T cell CD4 receptor C terminal region
Structure domains: transmembrane domain of human cd4

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 100%
Refinement method: torsion angle dynamics
Chemical shifts: BMR16853  
Expression system: Escherichia coli