PDBe 2kfv

Solution NMR

Structure of the amino-terminal domain of human FK506-binding protein 3 / Northeast Structural Genomics Consortium Target HT99A

Released:
Source organism: Homo sapiens
Entry authors: Sunnerhagen M, Davis T, Gutmanas A, Fares C, Ouyang H, Lemak A, Li Y, Weigelt J, Bountra C, Edwards A, Arrowsmith CH, Dhe-Paganon S, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0). 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase FKBP3 Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00688 (Residues: 1-73; Coverage: 33%)
Gene names: FKBP25, FKBP3

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: molecular dynamics
Chemical shifts: BMR16189  
Expression system: Escherichia coli