PDBe 2k2m

Solution NMR

Structural Basis of PxxDY Motif Recognition in SH3 Binding

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epidermal growth factor receptor kinase substrate 8-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TE68 (Residues: 481-536; Coverage: 8%)
Gene names: DRC3, EPS8L1, EPS8R1, PP10566
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: torsion angle dynamics
Chemical shifts: BMR15710  
Expression system: Escherichia coli