PDBe 2k0f

Solution NMR

Calmodulin complexed with calmodulin-binding peptide from smooth muscle myosin light chain kinase

Released:

Function and Biology Details

Reaction catalysed:
ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphate. 
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-2 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP24 (Residues: 2-149; Coverage: 99%)
Gene names: CALM2, CAM2, CAMB
Myosin light chain kinase, smooth muscle, deglutamylated form Chain: B
Molecule details ›
Chain: B
Length: 19 amino acids
Theoretical weight: 2.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q15746 (Residues: 1742-1760; Coverage: 1%)
Gene names: MLCK, MLCK1, MYLK, MYLK1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: CHARMM
Expression systems:
  • Escherichia coli
  • Not provided