PDBe 2jxr

X-ray diffraction
2.4Å resolution

Function and Biology Details

Reaction catalysed:
Hydrolysis of proteins with broad specificity for peptide bonds. Cleaves -Leu-Leu-|-Val-Tyr- bond in a synthetic substrate. Does not act on esters of Tyr or Arg. 
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Saccharopepsin Chain: A
Molecule details ›
Chain: A
Length: 329 amino acids
Theoretical weight: 35.77 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: P07267 (Residues: 77-405; Coverage: 86%)
Gene names: P2585, PEP4, PHO9, PRA1, YPL154C
Sequence domains: Eukaryotic aspartyl protease
Structure domains: Acid Proteases

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P3221
Unit cell:
a: 86.7Å b: 86.7Å c: 110.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.193 0.193 0.27
Expression system: Not provided