PDBe 2jxc

Solution NMR

Structure of the EPS15-EH2 Stonin2 Complex

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Stonin-2 Chain: B
Molecule details ›
Chain: B
Length: 45 amino acids
Theoretical weight: 4.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WXE9 (Residues: 301-340; Coverage: 4%)
Gene names: STN2, STNB, STON2
Epidermal growth factor receptor substrate 15 Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 10.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P42566 (Residues: 121-215; Coverage: 11%)
Gene names: AF1P, EPS15
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, torsion angle dynamics
Chemical shifts: BMR15554  
Expression system: Escherichia coli BL21(DE3)