PDBe 2jtt

Solution NMR

Solution structure of calcium loaded S100A6 bound to C-terminal Siah-1 interacting protein


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein S100-A6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 10.17 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli
  • Canonical: P30801 (Residues: 1-90; Coverage: 100%)
Gene name: S100A6
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand
Calcyclin-binding protein Chains: C, D
Molecule details ›
Chains: C, D
Length: 35 amino acids
Theoretical weight: 3.95 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9CXW3 (Residues: 189-219; Coverage: 14%)
Gene names: Cacybp, Sip

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 47%
Refinement method: simulated annealing
Chemical shifts: BMR15418  
Expression systems:
  • Escherichia coli
  • Escherichia coli BL21(DE3)