EC 1.1.1.44: Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)
Reaction catalysed:
6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH
Systematic name:
6-phospho-D-gluconate:NADP(+) 2-oxidoreductase (decarboxylating)
Alternative Name(s):
- 6-phospho-D-gluconate dehydrogenase
- 6-phosphogluconate dehydrogenase (decarboxylating)
- 6-phosphogluconic carboxylase
- 6-phosphogluconic dehydrogenase
- 6PGD
- Phosphogluconic acid dehydrogenase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR008927
Domain description:
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
Occurring in:
Occurring in:
Structure domains
CATH domains
1.10.1040.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Homology:
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Occurring in:
3.40.50.720
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Rossmann fold
Homology:
NAD(P)-binding Rossmann-like Domain
Occurring in:
