PDBe 2jj3

X-ray diffraction
2.28Å resolution

Estrogen receptor beta ligand binding domain in complex with a Benzopyran agonist

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Estrogen receptor beta Chains: A, B
Molecule details ›
Chains: A, B
Length: 257 amino acids
Theoretical weight: 29.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92731 (Residues: 251-505; Coverage: 48%)
Gene names: ESR2, ESTRB, NR3A2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P61
Unit cell:
a: 63.409Å b: 63.409Å c: 248.907Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.235 0.255
Expression system: Escherichia coli BL21(DE3)