PDBe 2jii

X-ray diffraction
2Å resolution

Structure of vaccinia related kinase 3

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inactive serine/threonine-protein kinase VRK3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 352 amino acids
Theoretical weight: 39.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8IV63 (Residues: 138-474; Coverage: 71%)
Gene name: VRK3
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 91.258Å b: 54.423Å c: 91.822Å
α: 90° β: 91.22° γ: 90°
R-values:
R R work R free
0.181 0.179 0.223
Expression system: Escherichia coli BL21