Function and Biology

REDUCED BRIDGE-BROKEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE

Source organism: Saccharomyces cerevisiae
Biochemical function: superoxide dismutase activity
Biological process: cellular oxidant detoxification
Cellular component: cytoplasm

EC 1.15.1.1: Superoxide dismutase

Reaction catalysed:
2 superoxide + 2 H(+) = O(2) + H(2)O(2).
Systematic name:
Superoxide:superoxide oxidoreductase
Alternative Name(s):
  • Cu,Zn-SOD
  • Cu-Zn superoxide dismutase
  • Fe-SOD
  • Mn-SOD
  • SOD
  • SOD-1
  • SOD-2
  • SOD-3
  • SOD-4
  • SODF
  • SODS
  • Copper-zinc superoxide dismutase
  • Cuprein
  • Cytocuprein
  • Erythrocuprein
  • Ferrisuperoxide dismutase
  • Hemocuprein
  • Hepatocuprein
  • Superoxidase dismutase
  • Superoxide dismutase I
  • Superoxide dismutase II

Sequence family

CATH Protein family (Pfam)
PF00080
Domain description: Copper/zinc superoxide dismutase (SODC)
Occurring in:
  1. Superoxide dismutase [Cu-Zn]
1 copy of Pfam domain PF00080 (Copper/zinc superoxide dismutase (SODC)) in Superoxide dismutase [Cu-Zn] in PDB 2jcw.

CATH InterPro annotations
IPR001424
Domain description: Superoxide dismutase, copper/zinc binding domain
Occurring in:
  1. Superoxide dismutase [Cu-Zn]
IPR018152
Domain description: Superoxide dismutase, copper/zinc, binding site
Occurring in:
  1. Superoxide dismutase [Cu-Zn]

Structure domain

CATH CATH domain
2.60.40.200
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulin-like
Occurring in:
  1. Superoxide dismutase [Cu-Zn]
1 copy of CATH domain 2.60.40.200 (Immunoglobulin-like) in Superoxide dismutase [Cu-Zn] in PDB 2jcw.
SCOP SCOP annotation
49330
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Cu,Zn superoxide dismutase-like
Occurring in:
  1. Superoxide dismutase [Cu-Zn]
1 copy of SCOP domain 49330 (Cu,Zn superoxide dismutase-like) in Superoxide dismutase [Cu-Zn] in PDB 2jcw.