PDBe 2j6o

X-ray diffraction
2.23Å resolution

ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETEROTRIMER

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CD2-associated protein Chain: A
Molecule details ›
Chain: A
Length: 62 amino acids
Theoretical weight: 7.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y5K6 (Residues: 1-62; Coverage: 10%)
Gene name: CD2AP
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains
T-cell surface antigen CD2 Chain: C
Molecule details ›
Chain: C
Length: 10 amino acids
Theoretical weight: 1.12 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P06729 (Residues: 324-333; Coverage: 3%)
Gene names: CD2, SRBC

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: I422
Unit cell:
a: 66.391Å b: 66.391Å c: 68.736Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.241 0.286
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided