PDBe 2ixn

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF THE PP2A PHOSPHATASE ACTIVATOR Ypa2 PTPA2

Released:

Function and Biology Details

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0). 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein phosphatase 2A activator 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 310 amino acids
Theoretical weight: 36.34 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12461 (Residues: 1-309; Coverage: 86%)
Gene names: NOH1, RRD2, YPA2, YPL152W
Sequence domains: Phosphotyrosyl phosphate activator (PTPA) protein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2221
Unit cell:
a: 157.93Å b: 171.042Å c: 53.735Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.199 0.273
Expression system: Escherichia coli